Medical castration with LHRH agonists is Body Cleanser a significant trend in the treatment of locally advanced and metastatic prostate cancer (PC).The article is devoted to the effectiveness of synthetic LHRH agonist buserelin (Buserelin-depo) in the treatment of patients with hormone dependent PC.Administration of Buserelin-depot Flux results in a decrease of the prostate-specific antigen levels, stable reduction of serum testosterone to postcastration level, reduction in the size of the prostate and fewer voiding dysfunction symptoms without any serious side effects.